Galactic Civilizations - I spent hundreds of hours play Galciv I on OS/2. Stardock just keeps making the game better, too bad they don't do multiplayer!
Conquest & Destiny - in development, if this game is half as kewl as it was 6 years ago as a text only massively multiplayer email game it's gonna rawk!
MAME (Multi Arcade Machine Emulator)
I have two arcade cabinets, I am going to build one of these...