Wellbutrin XL NDA 21-515

860 Around the eyes, swelling of the lips or tongue, chest pain, or have trouble breathing. These

861 could be signs of a serious allergic reaction.

862 ● Unusual thoughts or behaviors. Some patients have unusual thoughts or behaviors while

863 taking WELLBUTRIN XL, including delusion (believe you are someone else),

864 hallucinations (seeing or hearing things that are not there), paranoia (feeling that people are

865 against you), or feeling confused. If this happens to you, call your doctor.

866

867 The most common side effects of WELLBUTRIN XL are weight loss, loss of appetite, dry

868 mouth, skin rash, sweating, ringing in the ears, shakiness, stomach pain, agitation, anxiety,

869 dizziness, trouble sleeping, muscle pain, nausea, fast heartbeat, sore throat, and urinating more

870 often.

871

872 If you have nausea, take your medicine with food. If you have trouble sleeping, do not take you

873 medicine too close to bedtime.

874

875 Tell your doctor right away about any side effects that bother you.

876

877 These are not all the side effects of WELLBUTRIN XL. For a complete list, ask your doctor or

878 pharmacist.

879

880 How should I store WELLBUTRIN XL?

881 ● Store WELLBUTRIN XL at room temperature. Store out of direct sunlight. Keep

882 WELLBUTRIN XL in its tightly closed bottle.

883 ● WELLBUTRIN XL tablets may have an odor.

884

885 General Information about WELLBUTRIN XL.

886 ● Medicines are sometimes prescribed for conditions that are not mentioned in patient

887 information leaflets. Do not use WELLBUTRIN XL for a condition for which it was not

888 prescribed. Do not give WELLBUTRIN XL to other people, even if they have the same

889 symptoms you have. It may harm them. Keep WELLBUTRIN XL out of the reach of

890 children.

891

892 This leaflet summarizes important information about WELLBUTRIN XL. For more information

893 talk with your doctor. You can ask your doctor or pharmacist for information about

894 WELLBUTRIN XL that is written for health professionals or you can visit

895 www.wellbutrin-xl.com or call toll-free 888-825-5249.

896

897 What are the ingredients in WELLBUTRIN XL?

898 Active ingredient: bupropion hydrochloride.