Grey matter diseases

• Degenerative developmental diseases involving the grey matter of the central nervous system (brain and spinal cord)
• present with early seizures
• early intellectual decline
• later, see spasticity

Selected Grey Matter Diseases

• Tay sachs Disease
• Sandoff's Disease
• Generalized Gangliosidosis
• Gaucher's Disease
• Neimann Pick Disease
• Ceroid Lipfuscinosis (Battens Disease)
• Leigh Disease
• Mucopolysaccharidosis