| Part 1: 1945 - 2290 | Part 2: 2291 - 2375 |
| Year | Event |
| 2293 | Praxis, a Klingon moon, is destroyed by a huge explosion. The Klingon economy is nearly paralyzed, military budgets have to be cut, too. This leads to the Khitomer peace talks. Klingon chancellor Gorkon is assassinated. The office is carried on by his daughter, Azetbur. The Enterprise-A is decommissioned. Kirk, Scott and McCoy retire. The new Enterprise-B, an Excelsior-Class starship, is commissioned. Captain Harriman assumes command. On her maiden voyage, the Enterprise encounters a powerful energy field, the Nexus. Captain Kirk is believed killed when an energy discharge causes a hull breach in the section where Kirk is working. |
| 2295 | The transport ship USS Jenolen is lost on her way to the Norpin colony. One of the passengers was Captain Montgomery Scott. |
| 2311 | The Tomed incident. War with the Romulans is prevented by 2nd Treaty of Algeron which forbids the Federation use of cloaking technology. The Romulans start a prolonged period of isolation lasting until 2364. |
| 2327 | Jean-Luc Picard graduates from Starfleet Academy. |
| 2328 | Planet Bajor is annexed by the Cardassian Union. |
| 2333 | Captain Jean-Luc Picard assumes command of USS Stargazer NCC-2893. |
| 2344 | USS Enterprise NCC-1701-C is destroyed near Narendra III. |
| 2346 | Worf's parents are killed by Romulans at the Khitomer massacre. Starfleet Officer Sergey Rozhenko adopts Worf. |
| 2355 | USS Stargazer is nearly destroyed by a Ferengi vessel in the Battle of Maxia. After having spent months in an escape pod, Picard is court-martialled but eventually acquitted. |
| 2357 | William T. Riker graduates from Starfleet Academy. His first assignment is aboard the unfortunate USS Pegasus. |
| 2361 | Riker, now serving aboard the Potemkin, participates in a rescue mission on planet Nervala III. A double is created by a transporter malfunction, living undiscovered on the planet until 2369. |
| 2363 | The third Enterprise, the NCC-1701-D is launched from the Utopia Planitia Fleet Yards under the command of Captain Jean-Luc Picard. Before transferred to the Enterprise, William Riker serves as executive officer aboard USS Hood. |
| 2364 | First known contact with the Ferengi. First contact with the Q. Natasha Yar, tactical officer aboard the Enterprise is killed on planet Vagra II. An extragalactic conspiracy is uncovered in attempting to infiltrate Starfleet Command. |
| 2365 | Katherine Pulaski is Chief Medical Officer aboard the Enterprise. First contact with the Borg. |
| 2366 | The starship Enterprise-C briefly appears in the present by means of a temporal rift. Lieutenant Worf accepts dishonoring for sins his deceased father has (allegedly) committed against the Klingon Empire. Captain Picard is abducted and assimilated by the Borg. |
| 2367 | As Borg drone "Locutus", Picard is forced to lead an assault against the Federation near Wolf 359. In this battle, 39 out of 40 Starfleet vessels are destroyed. Alexander Rozhenko, son of Worf and K'Ehleyr, is born. Wesley Crusher enrolls at Starfleet Academy. Jean-Luc Picard serves as Arbiter of Succession to choose the successor of the assassinated Klingon chancellor K'mpec. |
| 2368 | The Klingon house of Duras tries to seize control of the Klingon High Council and thereby triggers a civil war. After Romulan support for Duras' forces is cut off, they are quickly defeated by Gowron's supporters. Gowron is appointed leader of the High Council and Chancellor of the Klingon Empire. Ambassador Spock is spotted on Romulus. He is supporting the reunification of Romulus and Vulcan. Ambassador Sarek dies at the age of 203. Wesley Crusher confesses having participated in disguising a fatal accident at Starfleet Academy. He is deferred one year. |
| 2369 | Captain Montgomery Scott is found alive aboard USS Jenolen after having spent 74 years as a molecular pattern in the Jenolen's transporter buffer. The Cardassians withdraw their claim on Bajor. With the end of the occupation, the space station Terok Nor is abandoned, too. At the request of the Bajoran Provisional Government, Starfleet takes over the administration of the station, now called Deep Space Nine. Commander Benjamin Sisko is assigned to command DS9. The first stable wormhole is discovered near Bajor. After Kai Opaka's death in the Gamma Quadrant, a power struggle for the succession starts on Bajor. |
| 2370 | The Soong-type android Lore is dismantled after trying to lead the Borg into a new campaign. Scientists find out that extensive use of warp drive systems could damage the structure of subspace. A Federation-wide speed limit of Warp 5.0 is introduced. An extremist religious group on Bajor, called "The Circle", tries to overthrow the Bajoran Provisional Government. Vedek Winn is elected successor of Kai Opaka. The battle ship USS Defiant NX-74205 is commissioned. The Dominion from the Gamma Quadrant, beyond the Bajoran Wormhole, tangles with the whole Alpha Quadrant by destroying all ships on "their" side of the passage. They also destroy a Bajoran colony. |
| 2371 | The USS Defiant is assigned to Deep Space Nine to defend Bajor and the wormhole in case of a Dominion attack. USS Voyager disappears without a trace in a mission to the "Badlands". A joint fleet of starships from the Romulan Tal Shiar and the Cardassian Obsidian Order is completely destroyed in the attempt to annihilate the homeworld of the Founders of the Dominion. Benjamin Sisko is promoted Captain. Worf is promoted Lieutenant Commander. The Enterprise-D is destroyed by a Klingon Bird-of-Prey while the crew is trying to prevent a planet from being destroyed by a crazy scientist. |
| 2372 | The Cardassian military government is overthrown and replaced by a civil government: the Datapa Council. Relations between the Federation and the Klingon Empire deteriorate after the Klingons have started to invade the Cardassian Union. They terminate the Treaty of Khitomer. Lieutenant Commander Worf is transferred to Deep Space Nine. The sixth Enterprise, the NCC-1701-E, is commissioned. Captain Picard assumes command. |
| 2373 | The Cardassian Union joins the Dominion. The Klingons are driven out of Cardassian space. Gul Dukat becomes governor of the Cardassian Union. After months of minor border skirmishes, the Khitomer treaty of 2293 is re-signed by Federation and Klingons. The Borg start a new invasion on the UFP. The Enterprise under Picard prevents their plan to rewrite history by travelling back in time. The Romulan Star Empire, the Tholien Assembly, the Miradorn and the Bajoran Provisional Government sign nonaggression treaties with the Dominion. The conflict between Federation/Klingons and the Dominion leads to an open war. The Federation station Deep Space Nine is conquered by the Dominion after the Bajoran Wormhole was mined by Starfleet. |
| 2274 | Deep Space Nine is retaken by a joint Starfleet/Klingon fleet. The minefield around the wormhole is destroyed. Gul Dukat is arrested. Gul Damarr takes his place as governor. Gul Dukat escapes captivity. Starfleet finds out USS Voyager was not destroyed but ended up in the Delta Quadrant. After Starfleet uncovers Dominion plans to invade Romulus inspite of the nonaggression treaty, the Romulans join the Federation/Klingon alliance to fight the Dominion. Starfleet, the Klingons and the Romulans take the offensive by attacking and occupying a Cardassian outpost. Jadzia Dax is killed in the execution of her duty. |
| 2275 | The USS Defiant is destroyed. The Defiant-class starship USS Sao Paulo is assigned to DS9 and renamed Defiant. The war in the Alpha Quadrant ends with the Federation/Klingon/Romulan fleet invading Cardassia Prime. Prior to the victory, 800 million Cardassians were killed by Jem'Hadar soldiers. Lieutenant Commander Worf is appointed Klingon ambassador to the UFP. |