9d

322U66 HCl (mg/kg/day, po)

0

75

150

300

300^a

Average Fetal Body Weight (g) per Litter^c

#

3.642

3.890

3.643

3.616

3.686

±0.051

±0.167

±0.051

±0.045

±0.054

N=29

N=27

N=27

N=25

N=24

Average Male Fetal Body Weight (g) per Litter^c

#

3.723

3.985

3.744

3.703

3.748

±0.053

±0.164

±0.054

±0.046

±0.059

N=29

N=27

N=27

N=25

N=24

Average Female Fetal Body Weight (g) per Litter^c

3.541

3.630

3.549

3.543

3.808

±0.052

±0.048

±0.052

±0.042

±0.057

N=29

N=27

N=27

N=25

N=24

Repeated Measures:

Bartlett’s (p<0.0001); DOSE (p=0.0568); SEX (p≤0.0001); DOSExSEX (p=0.4502).

Average Fetal Crown Rump Length (mm) per Litter^c

35.5

36.3

35.7

35.5

35.6

±0.3

±0.4

±0.2

±0.2

±0.2

N=29

N=27

N=27

N=25

N=24

Average Male Fetal Crown Rump Length (mm) per Litter^c

25.8

36.6

28.1

35.8

35.8

±0.3

±0.4

±0.2

±0.2

±0.2

N=29

N=27

N=27

N=25

N=24

Average Female Fetal Crown Rump Length (mm) per Litter^c

35.1

35.5

35.2

35.2

35.2

±0.3

±0.2

±0.3

±0.3

±0.2

N=29

N=27

N=27

N=25

N=24

Repeated Measures:

Bartlett’s (p=0.0113); DOSE (p=0.2189); SEX (p≤0.0001); DOSExSEX (p=0.7016).