Information on Antibiotics Used for Lyme Disease
Includes MEDLINE Adverse Effects

(Includes a Preliminary Accounting of Adverse Effects
with Emphasis on Drug Induced Neuropathy)

Lyme disease is a serious bacterial infection caused by a tick bite and affects humans and animals.

Links on this page labeled "MEDLINE" are links to citations of medical and scientific articles from the National Institutes of Health (NIH), National Library of Medicine (NLM) MEDLINE database.

Note: In the link titles below, the phrase, "1 of 2 on 29 Sep 99", for example, indicates that after reading the two citations found, only one refers to neuropathy as an adverse effect.

Table of Contents

Amoxicillin
Amoxicillin/clavulanate (Augmentin)
Azithromycin (Zithromax)
Cefotaxime (Claforan)
Ceftriaxone (Rocephin)
Cefuroxime axetil (Ceftin)
Clarithromycin (Biaxin)
Doxycycline
Metronidazole (Flagyl)
Penicillin G/benzylpenicillin/benzathine
Tetracycline

Resources for the information in this document
Other useful resources for drug information

For more information on antibiotics and Lyme disease
For more information on Lyme disease


Information on Antibiotics Used for Lyme Disease

Amoxicillin

Medscape - Drugs: Generic Drug Queries - Amoxicillin
Amoxicillin - RxList Monographs
Amoxicillin
Everything you ever wanted to know about Amoxicillin (but were too sick to ask)

MEDLINE - amoxicillin AND Lyme disease - 76 on 30 Sep 99

Adverse effects for amoxicillin

MEDLINE - amoxicillin [in Title] AND adverse effects [in Title] - 8 on 30 Sep 99
MEDLINE - amoxicillin AND adverse effects [in Title] - 29 on 30 Sep 99
MEDLINE - amoxicillin [in Title] AND adverse effects - 703 on 30 Sep 99
MEDLINE - amoxicillin AND adverse effects AND neuropathy - 1 (remote) on 30 Sep 99
MEDLINE - amoxicillin AND adverse effects - 1,496 on 30 Sep 99
MEDLINE - amoxicillin - 6093 on 30 Sep 99



Amoxicillin/clavulanate (Augmentin)

Augmentin(r) Information
Medscape - Drugs: Generic Drug Queries - Augmentin
Amoxicillin / Clavulanate - RxList Monographs
Amoxicillin and Potassium clavulanate

MEDLINE - amoxicillin/clavulanate (Augmentin) AND Lyme disease - 4 on 30 Sep 99

Adverse effects for amoxicillin/clavulanate (Augmentin)

MEDLINE - amoxicillin/clavulanate(Augmentin)[in Title]ANDadverse effects[in Title]-3on30Sep99
MEDLINE - amoxicillin/clavulanate (Augmentin) AND adverse effects [in Title] - 3 on 30 Sep 99
MEDLINE - amoxicillin/clavulanate (Augmentin) [in Title] AND adverse effects - 110 on 30Sep99
MEDLINE - amoxicillin/clavulanate(Augmentin)ANDadverse effectsANDneuropathy-0on30Sep99
MEDLINE - amoxicillin/clavulanate (Augmentin) AND adverse effects - 339 on 30 Sep 99
MEDLINE - amoxicillin/clavulanate (Augmentin) - 1,426 on 30 Sep 99



Azithromycin (Zithromax)

Pfizer Inc - Zithromax IV U.S. Product Prescribing Information
Pfizer Inc - Zithromax Tablets U.S. Product Prescribing Information
Medscape - Drugs: Generic Drug Queries - azithromycin
Azithromycin - RxList Monographs
Azithromycin

MEDLINE - azithromycin (Zithromax) AND Lyme disease - 33 on 30 Sep 99

Adverse effects for azithromycin (Zithromax)

MEDLINE - azithromycin (Zithromax) [in Title] AND adverse effects [in Title] - 1 on 30 Sep 99
MEDLINE - azithromycin (Zithromax) AND adverse effects [in Title] - 4 on 30 Sep 99
MEDLINE - azithromycin (Zithromax) [in Title] AND adverse effects - 213 on 30 Sep 99
MEDLINE - azithromycin (Zithromax) AND adverse effects AND neuropathy - 0 on 30 Sep 99
MEDLINE - azithromycin (Zithromax) AND adverse effects - 288 on 30 Sep 99
MEDLINE - azithromycin (Zithromax) - 1,279 on 30 Sep 99



Cefotaxime (Claforan)

Claforan(r) (cefotaxime sodium)
Medscape - Drugs: Generic Drug Queries - cefotaxime
Cefotaxime - RxList Monographs
Cefotaxime sodium

MEDLINE - cefotaxime [3rd generation] (Claforan) AND Lyme disease-170 on 30 Sep 99

Adverse effects for cefotaxime (Claforan)

MEDLINE - cefotaxime (Claforan) [in Title] AND adverse effects [in Title] - 3 on 30 Sep 99
MEDLINE - cefotaxime (Claforan) AND adverse effects [in Title] - 13 on 30 Sep 99
MEDLINE - cefotaxime (Claforan) [in Title] AND adverse effects - 283 on 30 Sep 99
MEDLINE - cefotaxime (Claforan) AND adverse effects AND neuropathy - 0 of 4 on 30 Sep 99
MEDLINE - cefotaxime (Claforan) AND adverse effects - 1,790 on 30 Sep 99
MEDLINE - cefotaxime (Claforan) - 8816 on 30 Sep 99



Ceftriaxone (Rocephin)

Roche U.S. Pharmaceuticals : Our Products : Rocephin(r): Complete Product Information
Medscape - Drugs: Generic Drug Queries - ceftriaxone
Ceftriaxone sodium

MEDLINE-ceftriaxone [3rd generation] (Rocephin) AND Lyme disease-218 on 30 Sep 99

Adverse effects for ceftriaxone (Rocephin)

MEDLINE - ceftriaxone (Rocephin) [in Title] AND adverse effects [in Title] - 3 on 30 Sep 99
MEDLINE - ceftriaxone (Rocephin) AND adverse effects [in Title] - 9 on 30 Sep 99
MEDLINE - ceftriaxone (Rocephin) [in Title] AND adverse effects - 371 on 30 Sep 99
MEDLINE - ceftriaxone (Rocephin) AND adverse effects AND neuropathy - 0 of 2 on 30 Sep 99
MEDLINE - ceftriaxone (Rocephin) AND gall bladder/stones AND Lyme disease-6 on 6 Jul 01
MEDLINE - ceftriaxone (Rocephin) AND gall bladder/stones - 57 on 6 Jul 01
MEDLINE - ceftriaxone (Rocephin) AND adverse effects - 573 on 30 Sep 99
MEDLINE - ceftriaxone (Rocephin) - 3265 on 30 Sep 99



Cefuroxime axetil (Ceftin)

Ceftin(r) (cefuroxime axetil tablets) Tablets [pdf file]
Medscape - Drugs: Generic Drug Queries - Ceftin
Cefuroxime - RxList Monographs
Cefuroxime axetil

MEDLINE-cefuroxime axetil [2nd generation] (Ceftin) AND Lyme disease-6 on 30 Sep 99

Adverse effects for cefuroxime axetil (Ceftin)

MEDLINE - cefuroxime axetil (Ceftin) [in Title] AND adverse effects [in Title] - 0 on 30 Sep 99
MEDLINE - cefuroxime axetil (Ceftin) AND adverse effects [in Title] - 0 on 30 Sep 99
MEDLINE - cefuroxime axetil (Ceftin) [in Title] AND adverse effects - 74 on 30 Sep 99
MEDLINE - cefuroxime axetil (Ceftin) AND adverse effects AND neuropathy - 1 on 30 Sep 99
MEDLINE - cefuroxime axetil (Ceftin) AND adverse effects - 98 on 30 Sep 99
MEDLINE - cefuroxime axetil (Ceftin) - 270 on 30 Sep 99



Clarithromycin (Biaxin)

Complete Biaxin Prescribing Information - Abbott Laboratories Inc. [24 pages - pdf]
Biaxin(r) - Abbott Pharmaceuticals Product Division
BIAXIN - Home Page - Abbott Laboratories Inc.
Medscape - Drugs: Generic Drug Queries - clarithromycin
Clarithromycin - RxList Monographs
Clarithromycin

MEDLINE - clarithromycin (Biaxin) AND Lyme disease - 15 on 30 Sep 99

Adverse effects for clarithromycin (Biaxin)

MEDLINE - clarithromycin (Biaxin) [in Title] AND adverse effects [in Title] - 2 on 30 Sep 99
MEDLINE - clarithromycin (Biaxin) AND adverse effects [in Title] - 7 on 30 Sep 99
MEDLINE - clarithromycin (Biaxin) [in Title] AND adverse effects - 315 on 30 Sep 99
MEDLINE - clarithromycin (Biaxin) AND adverse effects AND neuropathy - 0 on 30 Sep 99
MEDLINE - clarithromycin (Biaxin) AND adverse effects - 545 on 30 Sep 99
MEDLINE - clarithromycin (Biaxin) - 2,115 on 30 Sep 99



Doxycycline

Medscape - Drugs: Generic Drug Queries - doxycycline
Doxycycline - RxList Monographs
Doxycycline calcium

MEDLINE - doxycycline AND Lyme disease - 147 on 30 Sep 99

Adverse effects for doxycycline

MEDLINE - doxycycline [in Title] AND adverse effects [in Title] - 4 on 30 Sep 99
MEDLINE - doxycycline AND adverse effects [in Title] - 9 on 30 Sep 99
MEDLINE - doxycycline [in Title] AND adverse effects - 327 on 30 Sep 99
MEDLINE - doxycycline AND adverse effects AND neuropathy - 0 of 1 on 30 Sep 99
MEDLINE - doxycycline AND adverse effects - 692 on 30 Sep 99
MEDLINE - doxycycline - 3,893 on 30 Sep 99



Metronidazole (Flagyl)

Flagyl(r) 375 (metronidazole capsules)
Medscape - Drugs: Generic Drug Queries - Metronidazole
Metronidazole - RxList Monographs
Metronidazole

MEDLINE - metronidazole (Flagyl) AND Lyme disease - 2 on 30 Sep 99

Adverse effects for metronidazole (Flagyl)

MEDLINE - metronidazole (Flagyl) AND Lyme disease - 2 on 29 Sep 99
MEDLINE - metronidazole (Flagyl) [in Title] AND adverse effects [in Title] - 16 on 29 Sep 99
MEDLINE - metronidazole (Flagyl) AND adverse effects [in Title] - 26 on 29 Sep 99
MEDLINE - metronidazole (Flagyl) [in Title] AND adverse effects - 691 on 29 Sep 99
MEDLINE - metronidazole (Flagyl) AND adverse effects AND neuropathy - 28 on 29 Sep 99
MEDLINE - metronidazole (Flagyl) AND adverse effects AND stomach - 73 on 4 Oct 99
MEDLINE - metronidazole (Flagyl) AND adverse effects AND nausea OR vomiting-79on4Oct99
MEDLINE - metronidazole (Flagyl) AND adverse effects AND toxicity - 190 on 4 Oct 99
MEDLINE - metronidazole (Flagyl) AND adverse effects - 1,584 on 4 Oct 99
MEDLINE - metronidazole (Flagyl) - 8,186 on 29 Sep 99



Penicillin G/benzylpenicillin/benzathine

Medscape - Drugs: Generic Drug Queries - Penicillin G
Penicillin-G benzathine, parenteral

MEDLINE -
("penicillin g, benzathine"[MeSH Terms] OR Bicillin) AND LD - 7 on 22 May 01

MEDLINE - Penicillin G/benzylpenicillin AND Lyme disease - 139 on 30 Sep 99

Adverse effects for Penicillin G/benzylpenicillin/benzathine

MEDLINE - Penicillin G/benzylpenicillin [in Title] AND adverse effects [in Title] - 7 on 30 Sep 99
MEDLINE - Penicillin G/benzylpenicillin AND adverse effects [in Title] - 108 on 30 Sep 99
MEDLINE - Penicillin G/benzylpenicillin [in Title] AND adverse effects - 163 on 30 Sep 99
MEDLINE - Penicillin G/benzylpenicillin AND adverse effects AND neuropathy-0of1 on 30Sep99
MEDLINE - Penicillin G/benzylpenicillin AND adverse effects - 4,357 on 30 Sep 99
MEDLINE - Penicillin G/benzylpenicillin - 25,302 on 30 Sep 99



Tetracycline

Medscape - Drugs: Generic Drug Queries - tetracycline
Tetracycline HCl - RxList Monographs
Tetracycline

MEDLINE - tetracycline AND Lyme disease - 214 on 30 Sep 99

Adverse effects for tetracycline

MEDLINE - tetracycline [in Title] AND adverse effects [in Title] - 23 on 30 Sep 99
MEDLINE - tetracycline AND adverse effects [in Title] - 128 on 30 Sep 99
MEDLINE - tetracycline [in Title] AND adverse effects - 825 on 30 Sep 99
MEDLINE - tetracycline AND adverse effects AND neuropathy - maybe 1 of 2 on 30 Sep 99
MEDLINE - tetracycline AND adverse effects - 3,908 on 30 Sep 99
MEDLINE - tetracycline - 26,520 on 30 Sep 99



Resources for the information in this document:

Internet Grateful Med Search Screen
Medscape: Search DRUGS
RxList - The Internet Drug Index - RxList.com, Inc.
A-Z Drug Listing - The PDR Nurse's Drug Listing
Other useful resources for drug information:

Drugs: Multiple Drug-Drug Interactions
RXmed: Prescribing Information
Welcome to the Drug Database! - The PDR Nurse's Handbook Online Database



For more information on Lyme disease see: Lots Of Links On Lyme Disease

Comments or questions concerning this page should be directed to Art Doherty.

Last updated on 29 May 2000 by
Art Doherty
Lompoc, California
doherty@utech.net

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