| Pick | Team | Player | Position | School |
| 1 | |
Jake Long | OT | Michigan |
| 2 | |
Chris Long | DE | Virginia |
| 3 | |
Glenn Dorsey | DT | LSU |
| 4 | |
Darren McFadden | RB | Arkansas |
| 5 | |
Vernon Gholsten | DE | Ohio St |
| 6 | |
Jonathan Stewart | RB | Oregon |
| 7 | |
Derrick Harvey | DE | Florida |
| 8 | |
Matt Ryan | QB | Boston College |
| 9 | |
Sedrick Ellis | DT | USC |
| 10 | |
Keith Rivers | LB | USC |
| 11 | |
Leodis McKelvin | CB | Troy |
| 12 | |
Brandon Albert | OT | Virginia |
| 13 | |
Ryan Clady | OT | Boise St |
| 14 | |
Chris Williams | OT | Vanderbilt |
| 15 | |
Rashard Mendenhall | RB | Illinois |
| 16 | |
Dominique Rodgers-Cromartie | CB | Tennessee St |
| 17 | |
Jeff Otah | OT | Pittsburgh |
| 18 | |
Jerod Mayo | LB | Tennessee |
| 19 | |
Devin Thomas | WR | Michigan St |
| 20 | |
Desean Jackson | WR | California |
| 21 | |
Philip Merling | DE | Clemson |
| 22 | |
Kentwan Balmer | DT | North Carolina |
| 23 | |
Mike Jenkins | CB | USF |
| 24 | |
Limas Sweed | WR | Texas |
| 25 | |
Gosder Cherilus | OT | Boston College |
| 26 | |
Calais Campbell | DE | Miami |
| 27 | |
Quentin Groves | DE/OLB | Auburn |
| 28 | |
Felix Jones | RB | Arkansas |
| 29 | |
Lawrence Jackson | DE | USC |
| 30 | |
Brandon Flowers | CB | Virginia Tech |
| FORFEIT | forfeit | forfeit | forfeit | |
| 31 | |
Kenny Phillips | S | Miami |
| 32 | |
Curtis Lofton | ILB | Oklahoma |
| 33 | |
Aqib Talib | CB | Kansas |
| 34 | |
Brian Brohm | QB | Louisville |
| 35 | |
Tyrell Johnson | S | Arkansas St |
| 36 | |
Dan Connor | LB | Penn St |
| 37 | |
Sam Baker | OT | USC |
| 38 | |
Duane Brown | OT | Virginia Tech |
| 39 | |
Trevor Laws | DT | Notre Dame |
| 40 | |
Anthony Collins | OT | Kansas |
| 41 | |
James Hardy | WR | Indiana |
| 42 | |
Dustin Keller | TE | Purdue |
| 43 | |
Ray Rice | RB | Rutgers |
| 44 | |
Malcolm Kelly | WR | Oklahoma |
| 45 | |
Antoin Cason | CB | Arizona |
| 46 | |
Martellus Bennett | TE | Texas AM |
| 47 | |
Reggie Smith | S/CB | Oklahoma |
| 48 | |
Patrick Lee | CB | Auburn |
| 49 | |
Justin King | CB | Penn St |
| 50 | |
Tavares Gooden | OLB | Miami |
| 51 | |
Oneil Cousins | OT | OTEP |
| 52 | |
Eddie Royal | WR | Virginia Tech |
| 53 | |
Chilo Rachal | OG | USC |
| 54 | |
Tyvon Branch | CB | Connecticut |
| 55 | |
John Carlson | TE | Notre Dame |
| 56 | |
Fred Davis | TE | USC |
| 57 | |
Tracy Porter | CB | Indiana |
| 58 | |
Cliff Avril | DE | Purdue |
| 59 | |
Xavier Adibi | OLB | Virginia Tech |
| 60 | |
Shawn Crable | OLB | Michigan |
| 61 | |
Dre Moore | DT | Maryland |
| 62 | |
Matt Forte | RB | Tulane |