Cloning and Classification of Bt endotoxin Genes that Regulate Corn Borer Worm, in Thailand

 

Krit Pintong1, Pattana Srifah1, Pradit Pongtongkam1 and Jariya Chanpaisang2

1.      Genetics Department, Kasetsart University, Chatuchak, Bangkok 10900.

2.      Entomology Department, Kasetsart University, Chatuchak, Bangkok 10900.

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Cloning and classification of bt endotoxin gene from Bacillus Thuringiensis Thai isolates of JC276, JC281 and JC291, that test for regulate corn borer worms, in Thailand.  Two pair of Universal oligonucleotide primers were designed to amplified PCR Cry-type gene fragment of the DNA template from B.thuringiensis.  The amplified Cry gene products of all three isolate are 3 kilobase (K5Un3 and K3Un3 primers give 1.6 kilobase fragments and K5Un2 and K3Un2 primers give 1.4 kilobase fragments).  The restriction fragment length polymorphism (RFLP) pattern of PCR-amplified fragment revealed 3 possible distinct Cry-type genes included CryIA(a), CryIB and possible CryID or CryI(b) or Cry IF.  Among these the sequence of those genes were found to be different from the published Cry gene sequence.  Interestingly, Cry-type gene detect from B. thuringensis JC276 and JC281 were distinct from Cry-type gene from JC291.  However, all Cry-type genes isolate from Thai isolates are differed in gene sequencing from reported Cry-type gene in database.

 

 

PattanaDNA

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