CURRICULUM VITÆ

Breno Pannia Espósito

 

Place of birth: São Paulo, Brazil (October 21, 1971)

 

Present address:

 

Dept. of Biological Chemistry

Institute of Life Sciences

Hebrew University of Jerusalem

Jerusalem 91904                  Israel

Phone: 972-2-658 5441

Fax: 972-2-658 6974

breno@vms.huji.ac.il

 

Academic formation

 

Undergraduation:

Bachelor in Chemistry at the University of São Paulo (São Paulo, Brazil)

(1990 to 1994)

 

Graduation:

M.Sc. in Inorganic Chemistry at University of São Paulo

Title: “Study of the products of the reaction between rhodium (II) carboxylates and amides”

Supervisor: Prof. Dr. Renato Najjar

(1995 to 1997)

 

Ph.D. in Inorganic Chemistry at University of São Paulo

Title: “Interações de complexos de rodio(II) com albumina humana”

Supervisor: Prof. Dr. Renato Najjar

(1997 to 2000)

 

Pos-doctorate at the Department of Biological Chemistry, Hebrew University of Jerusalem (Israel)

Project: Fluorescence detection of intra and extracellular pools of iron.

Supervisor: Prof. Dr. Zvi Ioav Cabantchik

(2000 to 2002)

 

Academic production

 

Full papers:

 

Rh₂(CF₃CONH)₄: the first biologic assays of a rhodium (II) amidate

Espósito, B.P.; Souza, A.R.; Zyngier, S.B. and Najjar, R.

Metal-Based Drugs 1997, 4(6), 333-338

 

Increase in life span of mice bearing Ehrlich tumor treated with a rhodium (II) amidate

Zyngier, S.B.; Espósito, B.P.; Souza, A.R.; Najjar, R.

Naunyn-Schmiedeberg’s Archives of Pharmacology 1998, 358(1), R530, Suppl. 2

 

Survival and histopathological study of animals bearing Ehrlich tumor treated with a rhodium(II) amidate

Espósito, B.P.; Zyngier, S.B.; Najjar, R.; Paes, R.P.; Ueda, S.M.Y.; Barros, J.C.A.

Metal-Based Drugs 1999, 6(1), 17-18

 

A circular dichroism and fluorescence quenching study of the interactions between rhodium (II) complexes and human serum albumin

Espósito, B.P.; Faljoni-Alário, A.; Menezes, J.F.S.; Brito, H.F.; Najjar, R.

Journal of Inorganic Biochemistry 1999, 75(1), 55-61

 

Effects of human serum albumin in some biological properties of rhodium(II) complexes

Espósito, B.P.; Oliveira E., Zyngier, S.B.; Najjar R.

Journal of the Brazilian Chemical Society 2000, 11(5), 447-452

 

Labile iron in parenteral iron formulations and its potential for generating plasma non-transferrin bound iron (NTBI) in dialysis patients

Espósito, B.P.; Breuer, W.; Slotki, I.; Cabantchik, Z.I.

European Journal of Clinical Investigation 2002, 32 (Suppl.1), 42-49

 

Design and applications of methods for fluorescence detection of iron in biological systems

Espósito,B.P.; Breuer,W.; Cabantchik,Z.I.

Biochemical Society Transactions 2002, 30(4), 729-732

 

Reviews:

 

A review of fluorescence methods for assessing labile iron in cells and biological fluids

Espósito, B.P.; Epsztejn, S.; Breuer, W.; Cabantchik, Z.I.

Analytical Biochemistry 2002, 304,1-18

 

Interactions of antitumoral platinum-group metallodrugs with albumin

Espósito, B.P.; Najjar, R.

Coordination Chemistry Reviews 2002, 232(1-2), 139-151

 

Communications:

 

Hair tail fish (Trichiurus lepturus) at the Southeastern Brazilian Coast: yield, availability and evaluation of the nutritional potential

Panel at the 10^th Brazilian Meeting of Ichthyology (Feb, 1993)

Breno Pannia Espósito and Sérgio Araújo Antunes

Oceanographic Institute of University of São Paulo, Brazil

 

Study of the products of the reaction between rhodium (II) carboxylates and amides

Panel at the 19^th Annual Congress of the Brazilian Chemical Society (May, 1996)

Breno Pannia Espósito and Renato Najjar

Poços de Caldas, Brazil

 

Study of the biologic activity of a rhodium complex derived of trifluoroacetamide

Panel at the 20^th Annual Congress of the Brazilian Chemical Society (May, 1997)

Breno Pannia Espósito and Renato Najjar

Poços de Caldas, Brazil

Interaction of Rh₂(CF₃CONH)₄ with human serum albumin

Panel at the 21^st Annual Congress of the Brazilian Chemical Society (May, 1998)

Breno Pannia Espósito and Renato Najjar

Poços de Caldas, Brazil

 

Increase in life span of mice bearing Ehrlich tumor treated with a rhodium (II) amidate

Panel at the 13^th International Congress of Pharmacology (July, 1998)

Szulim Ber Zyngier, Breno Pannia Espósito, Aparecido Ribeiro de Souza and Renato Najjar

München, Germany

 

Design principles and applications of fluorescence detection of iron (FDI)

Plenary lecture at Biometals 2002: 3^rd International Biometals Symposium (April, 2002)

London, UK                             [Book of Abstracts, p 7]

 

Labile properties of non-transferrin-bound iron (NTBI) in iron overload and during chelation therapy

12^th International Conference on Oral Chelation in the Treatment of Thalassaemia and Other Diseases (ICOC) (July, 2002)

Breno Pannia Espósito, William Breuer, Pensri Pootrakul, Chaim Hershko and Zvi Ioav Cabantchik

Santorini, Greece             [Book of Abstracts, pp 27-29]

 

 

Academic traineeships

 

1) Sea food technology (1991 to 1993)

Oceanographic Institute of University of São Paulo

Supervisor: Prof. Dr. Sérgio Araújo Antunes

 

2) Theoretical chemistry (2nd half of 1993)

Institute of Chemistry of University of São Paulo

Supervisor: Prof. Dr. Eduardo Motta Alves Peixoto

 

3) Organic photochemistry (1994)

Institute of Chemistry of University of São Paulo

Supervisor: Prof. Dr. Luis Henrique Catalani

 

Industrial activities

 

Laboratory assistance at Givaudan-Roure of Brazil

Manipulation and development of flavorizants

(Dec, 1987 to Feb, 1990)