U.S. Federal Route 49 is a north-south surface highway in Central Craighead County. This is a surface highway through Metro-Jonesboro. U.S. Rt. 49 passes through the following towns in Craighead County. Jonesboro
Gibson Otwell
U.S. Rt. 49 is multi-plexed in Craighead County. U.S. Rt. 63B, at Joneboro. U.S. Rt. 63, at Jonesboro.
Branches of U.S. Rt. 49 in Craighead County. A junction marker on WB U.S. Rt. 63B/AR St Rt 18. A guide markers on AR St Rt 1B. A BGS on NB U.S. Rt. 49/SB U.S. Rt. 63. Another BGS on NB U.S. Rt. 49/SB U.S. Rt. 63. BGS on NB U.S. Rt. 63/SB U.S. Rt. 49. SB U.S. Rt. 49 guide marker. SB U.S. Rt. 49 on the southside of Jonesboro. SB U.S. Rt. 49 at Otwell.