| Captain Jean-Luc Picard | Patrick Stewart |
| Commander William T. Riker | Jonathan Frakes |
| Lt. Commander Data | Brent Spiner |
| Doctor Beverly Crusher | Gates McFadden |
| Conselor Deanna Troi | Marina Sirtis |
| Lt. Commander Worf | Michael Dorn |
| Lt. Commander Geordi La Forge | LeVar Burton |
| Lieutenant Natasha Yar (only 1st season) | Dinse Crosby |
| Doctor Kate Pulaski (only 2nd season) | Diana Muldar |
| Ensign Wesley Crusher (only seasons 1 through 4) | Wil Wheaton |
