When Billy Got shot by Andrew, we finally realized that something was wrong. I think Billy was quoted as saying " AHHHHHHHHHHH, Son of a…." Andrew still refused to Chrono his new gun.
The decision was made to take Andrew out, he just had to be stopped.
With Andrew gone, Missy and Delisa became the last line of defense. Missy was captured, but Delisa somehow managed to escape.
And in the most Bizarre incident in the game, Jason somehow fell and got his "black eye" He says it looked worse that what it was.