| Individual Records | |||||||
| Record | Setter | Date | |||||
| Most Goals in a Game | 3 | (3 tied) | |||||
| Most Assists in a Game | 4 | Campbell / Lydman | |||||
| Most Points in a Game | 5 | Drew Stafford | 1/18 vs. ATL | ||||
| Most Shots in a Game | 9 | Derek Roy | 1/18 vs. ATL | ||||
| Most PIMs in a Game | 12 | Paul Gaustad | 11/5 @ MTL | ||||
| Best +/- in a Game | +4 | Brian Campbell | 12/1 vs. CAR | ||||
| Game/Period Records | |||||||
| Record | Game | ||||||
| Most BUF Goals, Game | 10 | 1/18 vs. ATL | |||||
| Most Goals Combined, Game | 11 | 1/18 vs. ATL | |||||
| Most BUF Goals, Period | 4 | 10/13 vs. WSH, 2/12 @ OTT | |||||
| Most Goals Combined, Period | 7 | 2/25 vs. NSH | (2nd period) | ||||
| Most BUF SOG, Game | 53 | 10/13 vs. WSH | |||||
| Most SOG Combined, Game | 79 | 10/13 vs. WSH | |||||
| Most BUF SOG, Period | 24 | 10/13 vs. WSH | (2nd period) | ||||
| Most SOG Combined, Period | 35 | 1/30 @ FLA | (2nd period) | ||||
| Most BUF PIMs, Game | 32 | 10/11 vs. ATL | |||||
| Most PIMs Combined, Game | 65 | 2/27 vs. NSH | |||||
| Fewest BUF PIMs, Game | 2 | 1/6 @ ATL | |||||
| Fewest PIMs Combined, Game | 8 | 1/8 @ NJ | |||||
| Most PP Goals, Game | 4 | 10/11, 1/18 vs. ATL | |||||
| Rapid Scoring Records | |||||||
| Record | Setter | Game | |||||
| Quickest BUF Goal from Start of Game | 0:58 | Daniel Paille | 1/12 vs. NJ | ||||
| Quickest BUF Goal from Start of Period | 0:19 into 3rd | Drew Stafford | 12/14 @ WSH | ||||
| Quickest Two BUF Goals | 0:09 | Gaustad / Roy | 10/20 @ MTL | ||||
| Quickest Two BUF Goals, Same Player | 0:36 | Thomas Vanek | 2/20 vs. TB | ||||
| Quickest Three BUF Goals | 2:38 | Spacek / Afinogenov / Pominville | 10/13 vs. WSH | ||||
| Quickest Three BUF Goals, Same Player | 4:46 | Thomas Vanek | 2/20 vs. TB | ||||
| Quickest BUF Goal after an Opp. Goal | 0:15 | Ales Kotalik | 1/4 vs. OTT | ||||
| Team Streaks | |||||||
| Current Streak | 2 game losing streak | ||||||
| Longest Winning Streak | 6 games | Dec. 12 - Dec. 22 | |||||
| Longest Point Streak | 10 games (8-0-2 = 18 points) | Jan. 24 - Feb. 13 | |||||
| Longest Losing Streak | 3 games | Nov. 9 - Nov. 15 | |||||
| Longest Winless Streak | 10 games (0-5-5 = 5 points) | Dec. 26 - Jan. 16 | |||||
| Record | Setter | Result | |||||
| Largest Margin of Victory | 9 | 1/18 vs. ATL | 10-1 W | ||||
| Largest BUF Comeback | 2 w/ 2:21 left | 2/20 vs. TB | 4-3 W (OT) | ||||
| Largest BUF Comeback, 3rd Period | 2 w/ 2:21 left | 2/20 vs. TB | 4-3 W (OT) | ||||
| Record | Pt % | ||||||
| Record when Scoring First | 21-6-4 | 0.742 | |||||
| Record when Opp Scores First | 10-20-4 | 0.353 | |||||
| Record when Leading after 2 | 22-1-5 | 0.875 | |||||
| Record when Losing/Tied after 2 | 9-25-3 | 0.284 | |||||