You handle the Folio with reverance.
The greatest part of the work is eaten away by moths and mildew--it's a shame, really; this would be worth millions in mint condition. Yet some pieces exist--you see a famous monologue in a comedy titled As You Like It, small sections of both Julius Caesar and MacBeth , as well as a few scattered Cantos in back.
You tenderly place the old Folio down and move on to other literary works.