Medicinal Chemistry
CHEM 175 - Medicinal Chemistry

Text: "Pharmacology for Chemists", Joseph G. Cannon

References:

"Burger's Medicinal Chemistry and Drug Discovery"

"Principles of Medicinal Chemistry", William O. Foye

PharmInfoNet

Drug Information

PubMed (searchable database similar to MEDLINE and PREMEDLINE)

Format: T, Th lectures in CHPHB 101 (conference room) will, for the most part, cover the material in the same order as it is presented in the text. Weekly homework assignments will be collected and discussed in class. There will be a midterm exam in late October. Also, each student will give a 15-20 minute oral presentation summarizing their term paper (due at the end of the semester). Class participation will also contribute to your grade in the course.

Office hours: Wednesday and Thursday, 2 - 3 pm; room 313 CHPHB, Tel. 463-6577.

Date
Assignment
Topic
9/05 - 9/07 Ch 1 and Ch 2 General Concepts; Biological Membranes; General Anesthetics; Pharmacokinetics
9/12, 9/13 Ch 3 Drug Metabolism
9/19 - 9/21 Supplementary handout Structural Features and Biological Activity
9/26 and 9/28 Ch 4 Drug Receptor Interactions; Amino Acids and Proteins; Enzyme Receptor Sites
10/03 - 10/05 Ch 5 Principles of Pharmacological Assays
10/10 - 10/12 Ch 6 and supplementary handout Neurophysiology; Neurotransmission
10/17 - 10/19 Ch 7 Noradrenergic and Dopaminergic Nervous Systems
10/24 - 10/26 Ch 8 Cholinergic System
10/31 - 11/02 Ch 9 Psychotropic Drugs
11/07 - 11/09 Ch 10 and 13 Sedatives, Hypnotics and Anesthetics
11/14, 11/16 and 11/21 Ch 11 and 12 Analgesics
11/28 - 11/30 Ch 14 and 15 Cardiovascular System
12/05 and 12/07 Oral presentations
12/14 Final Exam
1